The match at DHL Newlands starts at 19h00 and will be televised live on the SuperSport Rugby and Grandstand channels.
Steyn missed last weekend's match against the Cell C Sharks due to a groin injury and although he is back in the starting line-up a call on his availability will only be made later. He is bracketed at inside centre with Chris Smit.
Meanwhile, Ian Groenewald will be making his debut in the place of JP du Preez at lock. The other change to the starting pack sees the selection of Phakisa Pumas recruit Jeandre Rudolph at No 8, in place of Aidon Davids.
Following a bright start to the campaign with 12 points from their first four matches, the Bloemfontein outfit returned to action last weekend with a 19-13 loss to the Cell C Sharks loss in Durban.
Now another tough away assignment awaits in Cape Town for the side coached by Hawies Fourie. The DHL Stormers won their last five games in a row against the Free Staters in Vodacom Super Rugby, dating back a few years.
The Toyota Cheetahs will be hoping for a good effort on defence as they are yet to concede a first-half try in the competition, conceding a total of just 12 first-half points.
Wilmar Arnoldi (cheek bone), Reniel Hugo (knee), Aranos Coetzee (ankle), Duncan Saal (hamstring), Ruan Pienaar (knee) and Craig Barry (knee) remain unavailable for selection because of injury.
Toyota Cheetahs: 15 Clayton Blommetjies, 14 Malcolm Jaer, 13 William Small-Smith, 12 Frans Steyn/Chris Smit, 11 Rosko Specman, 10 Tian Schoeman, 9 Tian Meyer, 8 Jeandré Rudolph, 7 Junior Pokomela (captain), 6 Andisa Ntsila, 5 Carl Wegner, 4 Ian Groenewald, 3 Luan de Bruin, 2 Reinach Venter, 1 Charles Marais. Replacements: 16 Boan Venter, 17 Marnus van der Merwe, 18 Khutha Mchunu, 19 JP du Preez, 20 Aidon Davis, 21 Ruben de Haas, 22 Reinhardt Fortuin, 23 Chris Smit/Howard Mnisi.
Match information – DHL Stormers v Toyota Cheetahs
Date: Saturday, 14 November
Venue: DHL Newlands, Cape Town
Referee: Marius van der Westhuizen
Assistant referees: Cwengile Jadezweni, Egon Seconds
Television Match Official: Joey Klaaste-Salmans
TV: SuperSport Rugby and Grandstand