Zak Burger will make a return to the starting team this week as the only change, where he will replace Embrose Papier in a rotational change at scrumhalf that sees the latter starting the match off the bench.
Cornal Hendricks, who was on Carling Currie Cup duty earlier in the week, has also been added to the replacements as backline cover, and he will be the only new player on the bench from the team that won at Emirates Airline Park last weekend.
"The result from last weekend when we beat the Emirates Lions at Emirates Airline Park will mean nothing," said Vodacom Bulls Director of Rugby, Jake White.
"It’s now a new week and they will come to Loftus Versfeld a hungry side and will want to make amends for the defeat last Saturday.
"We expect nothing less than another challenging encounter against the side from Johannesburg. They showed how strong they can be in the set pieces last week, while also coming at us with some clever, running rugby. We can definitely expect more of the same this weekend."
The match kicks off at 15h00, and it will be televised on SuperSport.
Vodacom Bulls: 15 Kurt-Lee Arendse, 14 Canan Moodie, 13 Lionel Mapoe, 12 Harold Vorster, 11 Madosh Tambwe, 10 Morné Steyn, 9 Zak Burger; 8 Elrigh Louw, 7 Arno Botha, 6 Marcell Coetzee (captain), 5 Ruan Nortje, 4 Walt Steenkamp, 3 Jacques van Rooyen, 2 Johan Grobbelaar, 1 Simphiwe Matanzima. Replacements: 16 Bismarck du Plessis, 17 Lizo Gqoboka, 18 Robert Hunt, 19 Janko Swanepoel, 20 Muller Uys, 21 Embrose Papier, 22 Chris Smith, 23 Cornal Hendricks.