The Vodacom Bulls - with a new captain in Nizaam Carr and some serious impact off the bench - are in action on Friday night in France against Lyon (22h00 SA time).
On Saturday, the Cell C Sharks face Harlequins in London (15h00 SA time) without the Springbok duo of Makazole Mapimpi (suspended) and Bongi Mbonambi (injured), before the DHL Stormers host ASM Clermont Auvergne in Cape Town (19h30) with a new halfback pairing of Stefan Ungerer and Kade Wolhuter, and the returning Evan Roos on the bench.
The two EPCR Challenge Cup games featuring SA teams hunting spots in the playoffs are both on Sunday.
The Emirates Lions have Jordan Hendrikse back at flyhalf when they take on Dragons in Newport, Wales at 15h00 (SA time), and the Toyota Cheetahs, under the captaincy of Victor Sekekete, take on Section Paloise in Parma, Italy at 17h15 (SA time).
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The teams are:
Vodacom Bulls: 15 Kurt-Lee Arendse, 14 Canan Moodie, 13 Wandisile Simelane, 12 Cornal Hendricks, 11 David Kriel, 10 Johan Goosen, 9 Embrose Papier, 8 Nizaam Carr (captain), 7 Cyle Brink, 6 Marco van Staden, 5 Janko Swanepoel, 4 Ruan Vermaak, 3 Francois Klopper, 2 Bismarck Du Plessis, 1 Simphiwe Matanzima. Replacements: 16 Johann Grobbelaar, 17 Gerard Steenekamp, 18 Mornay Smith, 19 Ruan Nortje, 20 Elrigh Louw, 21 Zak Burger, 22 Chris Smith, 23 Lionel Mapoe.
Cell C Sharks: 15 Aphelele Fassi, 14 Marnus Potgieter, 13 Lukhanyo Am, 12 Ben Tapuai, 11 Thaakir Abrahams, 10 Curwin Bosch, 9 Jaden Hendrikse, 8 Phepsi Buthelezi, 7 Vincent Tshituka, 6 Siya Kolisi (captain), 5 Gerbrandt Grobler, 4 Eben Etzebeth, 3 Thomas du Toit, 2 Kerron van Vuuren, 1 Ox Nche. Replacements: 16 Dan Jooste, 17 Ntuthuko Mchunu, 18 Carlu Sadie, 19 Hyron Andrews, 20 Sikhumbuzo Notshe, 21 Grant Williams, 22 Lionel Cronje, 23 Francois Venter.
DHL Stormers: 15 Damian Willemse, 14 Suleiman Hartzenberg, 13 Ruhan Nel, 12 Dan du Plessis, 11 Angelo Davids, 10 Kade Wolhuter, 9 Stefan Ungerer, 8 Hacjivah Dayimani, 7 Willie Engelbrecht, 6 Deon Fourie, 5 Marvin Orie, 4 Connor Evans, 3 Neethling Fouche, 2 Joseph Dweba, 1 Steven Kitshoff (captain). Replacements: 16 JJ Kotze, 17 Ali Vermaak, 18 Brok Harris, 19 Ben-Jason Dixon, 20 Evan Roos, 21 Herschel Jantjies, 22 Jean-Luc du Plessis, 23 Sacha Feinberg-Mngomezulu.
Emirates Lions: 15 Andries Coetzee, 14 Quan Horn, 13 Henco van Wyk, 12 Marius Louw (captain), 11 Edwill vd Merwe, 10 Jordan Hendrikse, 9 Andre Warner, 8 Emmanuel Tshituka, 7 Emile van Heerden, 6 Jaco Kriel, 5 Darrien Landsberg, 4 Willem Alberts, 3 Asenathi Ntlabakanye, 2 Michael van Vuuren, 1 JP Smith. Replacements: 16 PJ Botha, 17 Morgan Naude, 18 Ruan Smith, 19 Pieter Janse van Vuren, 20 Ruhan Straeuli, 21 JC Pretorius, 22 Morne vd Berg, 23 Rynhardt Jonker.
Toyota Cheetahs: 15 Tapiwa Mafura, 14 Daniel Kasende, 13 David Brits, 12 Reinhardt Fortuin, 11 Munier Hartzenberg, 10 Siya Masuku, 9 Rewan Kruger, 8 Jeandre Rudolph, 7 Friedle Olivier, 6 Daniel Maartens, 5 Victor Sekekete (captain), 4 Rynier Bernardo, 3 Aranos Coetzee, 2 Louis vd Westhuizen, 1 Schalk Ferreira. Replacements: 16 Marco Janse van Rensburg, 17 Alulutho Tshakweni, 18 Hencus van Wyk, 19 Mzwanele Zito, 20 Roelof Smit, 21 Branden de Kock, 22 Robert Ebersohn, 23 Andell Loubser.